Parkinson’s disease remains a clinical diagnosis and a reminder of the UK brain bank criteria can help ensure that our clinical diagnoses maintain a reasonable level of specificity. DaTSCANs™ can be helpful where diagnostic uncertainty remains, particularly in distinguishing Parkinson’s disease from drug induced parkinsonism, but are of no use in distinguishing from the Parkinson-plus disorders. New evidence is driving increasing numbers of Parkinson’s disease specialists to recommend earlier treatment for Parkinson’s disease; however, the choice of medication to initiate should still be tailored to the individual patient according to their disability.