Diabetes: newer agents for the older patient?

Introduction Hypoglycaemia Inevitable trajectory of type 2 diabetes Antihyperglycaemic therapy in type 2 diabetes Metformin Sulphonylureas Thiazolidinediones Incretin therapies SGLT2 inhibitors Conclusions References       Introduction Management of diabetes can sometimes be a balancing act between the benefits of treatment versus the risks. On one side we are trying to provide symptomatic relief for our patients, avoid admission into hospital and reduce risk of complications, but we are also trying to avoid hypoglycaemia, medication side effects and weight gain. A key question is does glycaemic control reduce complications? There have been a number of glycaemic interventions studies looking into