Management of late onset type 1 diabetes

First published September 2016, updated March 2022   IntroductionTreatment OptionsPrevention of complicationsWhat is DAFNE?References   Introduction Type 1 diabetes is an auto-immune condition characterised by insulin deficiency. The pathogenesis is immune-mediated destruction of the insulin producing beta cells of the islets of Langherhans in the pancreas. Typically, the onset is in childhood with a peak incidence in the early teenage years. However, true type 1 diabetes can occur at any age€”the oldest person in whom I have made the diagnosis was 92 years old. The presenting features of type 1 diabetes are those of hyperglycaemia and insulin deficiency. In young