New therapy could slow the progression of kidney disease in people with diabetes

A new discovery has the potential to slow the progression of kidney disease in people with diabetes and prevent renal failure by supporting the normal function of the mitochondria within the kidney. The five-year study initially discovered that a key immune system pathway €“ which usually protects the body from infection €“ was hyperactivated and caused inflammation in people with diabetic kidney disease. The team led by Associate Professor Melinda Coughlan from the Department of Diabetes then discovered this pathway could be disrupted with a drug (developed by Associate Professor Trent Woodruff, from the School of Biomedical Sciences at the University of