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Systemic amyloidosis with cardiac involvement

Amyloidosis is a term used to describe a group of disorders consisting of abnormalities in and the accumulation of amyloid protein. This protein cannot be degraded and so collects in the tissues, interrupting both their structure and function. The disorder is progressive as amyloid increases and symptoms vary depending on the affected organs, which can be localised or systemic. We discuss diagnosis and management of amyloidosis with cardiac involvement and describe a case presenting in late life with rapid progression. 

Amyloidosis is a term used to describe a group of disorders consisting of abnormalities in and the accumulation of amyloid protein. This protein cannot be degraded and so collects in the tissues, interrupting both their structure and function. The disorder is progressive as amyloid increases and symptoms vary depending on the affected organs, which can be localised or systemic. We discuss diagnosis and management of amyloidosis with cardiac involvement and describe a case presenting in late life with rapid progression.

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