Leaders in cardiovascular disease prevention and control have called for urgent action to reduce premature mortality by 25% by 2025. The paper published by the Global Cardiovascular Disease Taskforce, a group of eminent experts who represent five leading heart-health organisations, talks about an agreement by governments on a set of ambitious global targets to curb the growing scourge of non-communicable diseases (NCDs), which includes cardiovascular disease (CVD; heart disease and stroke), is critical to avoiding the millions of premature deaths worldwide. The Taskforce is calling on governments and the CVD community to accelerate progress on the commitments already made by supporting 10 evidence based targets. CVD is the leading cause of death worldwide, killing 17.3 million people a year and making up nearly half of the 36 million NCD deaths. Around 80% of these deaths are in low- and middle-income countries where human and financial resources are most limited to address them. The number of CVD deaths is expected to rise to 23.6 million by 2030. The Global CVD Taskforce suggests, additional targets developed by the World Health Organization (WHO) are key to achieving this overarching goal. These include curbing physical inactivity, tobacco consumption, salt intake and hypertension.