Concerns have arisen that antipsychotic medication is associated with adverse metabolic effects, such
as diabetes, weight gain, and dyslipidaemia. These drugs are used frequently in older people and as
many as half of all prescriptions for antipsychotics are estimated to be for people older than 65 years.
Furthermore, the incidence of diabetes and other metabolic disorders increases with age. Data from
randomised controlled trials and observational studies suggest that the rate of adverse events is lower
in older people on antipsychotics compared with younger individuals with schizophrenia. Nevertheless,
taking precautions is important when using these drugs in elderly patients. Blood-glucose and lipid
profiles should be checked before starting treatment, 3-4 months later, and then yearly.